J Todd Purves Selected Research

Myopia 3

10/2021	BOO induces fibrosis and EMT in urothelial cells which can be recapitulated in vitro through elevated storage and voiding pressure cycles.
9/2018	Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells.

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J Todd Purves Research Topics

Disease

18	Inflammation (Inflammations) 06/2022 - 01/2013
6	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 01/2019 - 02/2014
5	Fibrosis (Cirrhosis) 01/2022 - 01/2017
4	Wounds and Injuries (Trauma) 01/2022 - 02/2008
4	Cystitis 01/2020 - 01/2013
3	Infections 01/2020 - 12/2015
2	Myopia 3 10/2021 - 09/2018
2	Acute Lung Injury 01/2020 - 01/2020
2	Urinary Tract Infections (Urinary Tract Infection) 10/2019 - 02/2014
2	Hemorrhagic Cystitis 08/2013 - 09/2005
2	Bladder Exstrophy (Exstrophy, Bladder) 04/2008 - 02/2008
1	Pneumonia (Pneumonitis) 01/2020
1	Anhedonia 01/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020
1	Neuroinflammatory Diseases 01/2020
1	Diabetes Complications 01/2019
1	Urologic Diseases (Urinary Tract Disease) 02/2018
1	Hyperglycemia 01/2018
1	Polyuria 01/2018
1	Ganglion Cysts (Ganglion) 01/2018
1	Pelvic Pain 01/2017
1	Urinary Incontinence 01/2017
1	Urinary Calculi (Urinary Calculus) 10/2016
1	Hypertrophy 05/2016
1	Spinal Cord Injuries (Spinal Cord Injury) 08/2015
1	Contusions 08/2015
1	Hemorrhage 01/2013
1	Prolapse 09/2011
1	Epispadias 10/2008
1	Neoplasms (Cancer) 10/2008
1	Arthralgia (Joint Pain) 10/2008
1	Leg Length Inequality 10/2008

Drug/Important Bio-Agent (IBA)

13	InflammasomesIBA 06/2022 - 02/2014
7	Evans Blue (Blue, Evans)FDA Link 06/2022 - 01/2013
6	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2013
6	Glyburide (Glibenclamide)FDA LinkGeneric 01/2020 - 02/2014
3	CollagenIBA 01/2022 - 01/2017
2	Coloring Agents (Dyes)IBA 10/2021 - 02/2016
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 01/2020
2	NLR ProteinsIBA 01/2020 - 05/2016
2	CytokinesIBA 01/2020 - 02/2018
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2019 - 12/2015
2	Pyrin Domain-Containing 3 Protein NLR FamilyIBA 05/2016 - 02/2016
1	Blood Glucose (Blood Sugar)IBA 06/2022
1	5S,12R,18R- trihydroxy- 6Z,8E,10E,14Z,16E- eicosapentaenoic acidIBA 01/2022
1	Peptides (Polypeptides)IBA 10/2021
1	Sucrose (Saccharose)IBA 01/2020
1	Adenosine Triphosphate (ATP)IBA 09/2018
1	Interleukin-18 (Interleukin 18)IBA 02/2018
1	PyrinIBA 02/2018
1	Leucine (L-Leucine)FDA Link 02/2018
1	NucleotidesIBA 02/2018
1	PhlorhizinIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2017
1	trichrome stainIBA 01/2017
1	Silk FDA Link 05/2016
1	Ethanol (Ethyl Alcohol)IBA 05/2016
1	Caspase 1 (ICE Protease)IBA 02/2016
1	LigandsIBA 02/2016
1	LipopolysaccharidesIBA 02/2016
1	S-NitrosoglutathioneIBA 08/2015
1	Acrolein (Aqualin)IBA 08/2013
1	Mesna (Coenzyme M)FDA LinkGeneric 08/2013
1	Simvastatin (Zocor)FDA LinkGeneric 01/2013
1	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 09/2005

Therapy/Procedure

4	Therapeutics 01/2021 - 01/2013
4	Osteotomy 09/2011 - 02/2008
3	Drug Therapy (Chemotherapy) 02/2014 - 01/2013
2	Catheters 05/2016 - 02/2014
1	Antibiotic Prophylaxis 10/2019
1	Denervation 01/2018
1	Ligation 05/2016
1	Oral Administration 08/2015
1	Castration 10/2008
1	Cystectomy 02/2008